RECENT POSTS

Presence of the HPPD Inhibitor Sensitive 1 Gene and ALS(S653N) Mutation in Weedy Oryza sativa Sensitive to Benzobicyclon

18/11/2020
ALS


Disorders of sleep and wakefulness in amyotrophic lateral sclerosis (ALS): a systematic review

16/11/2020
ALS


Accumulation of Target Gene Mutations Confers Multiple Resistance to ALS, ACCase, and EPSPS Inhibitors in Lolium Species in Chile

16/11/2020
ALS


Ubiquitin Homeostasis Is Disrupted in TDP-43 and FUS Cell Models of ALS

16/11/2020
ALS


ALS motor neurons exhibit hallmark metabolic defects that are rescued by SIRT3 activation

13/11/2020
ALS


Chronic administration of P2X7 receptor antagonist JNJ-47965567 delays disease onset and progression, and improves motor performance in ALS SOD1(G93A) female mice

11/11/2020
ALS


Esophageal Peristalsis Disorders in ALS Patients with Dysphagia

11/11/2020
ALS


Macrophages - new targets in ALS?

11/11/2020
ALS


Nicotinamide Riboside and Pterostilbene Cooperatively Delay Motor Neuron Failure in ALS SOD1(G93A) Mice

11/11/2020
ALS


ALS-CSF-induced structural changes in spinal motor neurons of rat pups cause deficits in motor behaviour

11/11/2020
ALS


Generating broad-spectrum tolerance to ALS-inhibiting herbicides in rice by base editing

10/11/2020
ALS


ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS

08/11/2020
ALS


Copper-ATSM as a Treatment for ALS: Support from Mutant SOD1 Models and Beyond

07/11/2020
ALS


Neuroanatomical associations of the Edinburgh cognitive and Behavioural ALS screen (ECAS)

06/11/2020
ALS


Abstracts from the 31st International Symposium on ALS/MND

06/11/2020
ALS


Tetramethylpyrazine nitrone improves motor dysfunction and pathological manifestations by activating the PGC-1alpha/Nrf2/HO-1 pathway in ALS mice

06/11/2020
ALS


Overexpression of an ALS-associated FUS mutation in C. elegans disrupts NMJ morphology and leads to defective neuromuscular transmission

05/11/2020
ALS


Coexistence of perseveration and apathy in the TDP-43(Q331K) knock-in mouse model of ALS-FTD

05/11/2020
ALS


Sigma-1 receptor chaperones rescue nucleocytoplasmic transport deficit seen in cellular and Drosophila ALS/FTD models

05/11/2020
ALS


Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-B activators for the treatment of ALS

03/11/2020
ALS


RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3

02/11/2020
ALS


The genetic architecture of ALS

02/11/2020
ALS


Uniparental Disomy Leading to a Rare Juvenile Form of ALS

30/10/2020
ALS


L-tert-Leucin als Konstitutionsisomer der proteino-genen Aminosauren L-Leucin und L-Isoleucin: Herstellung sowie Vorkommen in Naturstoffen und als Baustein in Pharmaka

30/10/2020
ALS


A Nitroalkene Benzoic Acid Derivative Targets Reactive Microglia and Prolongs Survival in an Inherited Model of ALS via NF-kappaB Inhibition

30/10/2020
ALS


uren L-Leucin und L-Isoleucin: Herstellung sowie Vorkommen in Naturstoffen und als Baustein in Pharmaka

29/10/2020
ALS


A Nitroalkene Benzoic Acid Derivative Targets Reactive Microglia and Prolongs Survival in an Inherited Model of ALS via NF-κB Inhibition

29/10/2020
ALS


The stage is set for a new trial end point in ALS

28/10/2020
ALS


USP7 regulates ALS-associated proteotoxicity and quality control through the NEDD4L-SMAD pathway

27/10/2020
ALS


Pro-197-Ser Mutation in ALS and High-Level GST Activities: Multiple Resistance to ALS and ACCase Inhibitors in Beckmannia syzigachne

27/10/2020
ALS


Transport alteration of 4-phenyl butyric acid mediated by a sodium- and proton-coupled monocarboxylic acid transporter system in ALS model cell lines (NSC-34) under inflammatory states

25/10/2020
ALS


Hippocampal connectivity in Amyotrophic Lateral Sclerosis (ALS): more than Papez circuit impairment

23/10/2020
ALS


A Human iPSC Line Carrying a de novo Pathogenic FUS Mutation Identified in a Patient With Juvenile ALS Differentiated Into Motor Neurons With Pathological Characteristics

23/10/2020
ALS


Sleep in ALS: more than discomfort or respiratory breathing disorder

22/10/2020
ALS


ANXA11 mutations in ALS cause dysregulation of calcium homeostasis and stress granule dynamics

22/10/2020
ALS


Natural history and clinical features of ALS in Malaysia

22/10/2020
ALS


Selective neuronal degeneration in MATR3 S85C knock-in mouse model of early-stage ALS

21/10/2020
ALS


Identification of a pathogenic intronic KIF5A mutation in an ALS-FTD kindred

21/10/2020
ALS


Multiple mutations in the EPSPS and ALS genes of Amaranthus hybridus underlie resistance to glyphosate and ALS inhibitors

21/10/2020
ALS


Help from peripheral macrophages in ALS?

21/10/2020
ALS


Modifying macrophages at the periphery has the capacity to change microglial reactivity and to extend ALS survival

21/10/2020
ALS


Insight into the autosomal-dominant inheritance pattern of SOD1-associated ALS from native mass spectrometry

20/10/2020
ALS


Rapid progressive ALS in a patient with a DNAJC7 loss-of-function mutation

20/10/2020
ALS


Long-Term Survival of Participants in the CENTAUR Trial of Sodium Phenylbutyrate-Taurursodiol in ALS

20/10/2020
ALS


ALS-Related Mutant SOD1 Aggregates Interfere with Mitophagy by Sequestering the Autophagy Receptor Optineurin

20/10/2020
ALS


Direct quantification of protein dimerization preference shed light on SOD1-associated ALS

20/10/2020
ALS


TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

09/10/2020
ALS


Overexpression of UBQLN1 reduces neuropathology in the P497S UBQLN2 mouse model of ALS/FTD

08/10/2020
ALS


Prime editing efficiently generates W542L and S621I double mutations in two ALS genes in maize

07/10/2020
ALS


Knock in of a hexanucleotide repeat expansion in the C9orf72 gene induces ALS in rats

07/10/2020
ALS


ALS-Linked Mutant SOD1 Associates with TIA-1 and Alters Stress Granule Dynamics

07/10/2020
ALS


Survival and Motor Phenotypes in FVB C9-500 ALS/FTD BAC Transgenic Mice Reproduced by Multiple Labs

07/10/2020
ALS


Behavioral, Hormonal, Inflammatory, and Metabolic Effects Associated with FGF21-Pathway Activation in an ALS Mouse Model

07/10/2020
ALS


The ALS-related σ1R E102Q Mutant Eludes Ligand Control and Exhibits Anomalous Response to Calcium

06/10/2020
ALS


Commentary: Effects of ALS-associated TANK binding kinase 1 mutations on protein-protein interactions and kinase activity

05/10/2020
ALS


A repeating theme in ALS genetics

02/10/2020
ALS


Age-dependent degeneration of an identified adult leg motor neuron in a Drosophila SOD1 model of ALS

01/10/2020
ALS


Genetic inactivation of RIP1 kinase does not ameliorate disease in a mouse model of ALS

01/10/2020
ALS


Unusual electrophysiological findings in a Chinese ALS 4 family with SETX-L389S mutation: a three-year follow-up

01/10/2020
ALS


IAP ALS Update on Resuscitation Guidelines During COVID-19 Pandemic

30/09/2020
ALS


A Non-invasive Digital Biomarker for the Detection of Rest Disturbances in the SOD1G93A Mouse Model of ALS

30/09/2020
ALS


CSF Neurofilament Light Chain Elevation Predicts ALS Severity and Progression

30/09/2020
ALS


Cardiovascular disease, psychiatric diagnosis and sex-differences in the multi-step hypothesis of ALS

26/09/2020
ALS


Exploring Multiple Sclerosis (MS) and Amyotrophic Lateral Sclerosis (ALS) as neurodegenerative diseases and their treatments: A review

25/09/2020
ALS


Inducible EphA4 knockout causes motor deficits in young mice and is not protective in the SOD1(G93A) mouse model of ALS

25/09/2020
ALS


A Phase 2, Double-Blind, Randomized, Dose-Ranging Trial Of Reldesemtiv In Patients With ALS

24/09/2020
ALS


Investigation of the binding properties between levamlodipine and HSA based on MCR-ALS and computer modeling

23/09/2020
ALS


Quality-control mechanisms targeting translationally stalled and C-terminally extended poly(GR) associated with ALS/FTD

22/09/2020
ALS


Clinical and Molecular Landscape of ALS Patients with SOD1 Mutations: Novel Pathogenic Variants and Novel Phenotypes. A Single ALS Center Study

20/09/2020
ALS


Recovery of trace evidence in forensic archaeology and the use of alternate light sources (ALS)

20/09/2020
ALS


Frequent self-assessments in ALS Clinical Trials: worthwhile or an unnecessary burden for patients?

18/09/2020
ALS


Reply to: Frequent self-assessments in ALS clinical trials: Worthwhile or an unnecessary burden?

18/09/2020
ALS


"Re-identifying yourself": a qualitative study of veteran views on implantable BCI for mobility and communication in ALS

17/09/2020
ALS


ALS Genetics: Gains, Losses, and Implications for Future Therapies

16/09/2020
ALS


Palliative care, evidence, and ALS: The baby and the bathwater

16/09/2020
ALS


Predictive factors for prognosis after gastrostomy placement in routine non-invasive ventilation users ALS patients

16/09/2020
ALS


Aggregate-selective antibody attenuates seeded aggregation but not spontaneously evolving disease in SOD1 ALS model mice

16/09/2020
ALS


Portable and benchtop Raman spectrometers coupled to cluster analysis to identify quinine sulfate polymorphs in solid dosage forms and antimalarial drug quantification in solution by AuNPs-SERS with MCR-ALS

16/09/2020
ALS


Phenotypic diversity in ALS and the role of poly-conformational protein misfolding

16/09/2020
ALS


Safety of Gastrostomy Tube Placement in Advanced ALS Patients with Non-invasive Ventilation

15/09/2020
ALS


The herbal extract ALS-L1023 from Melissa officinalis reduces weight gain, elevated glucose levels and β-cell loss in Otsuka Long-Evans Tokushima fatty rats

15/09/2020
ALS


Degeneration of gray and white matter differs between hypometabolic and hypermetabolic brain regions in a patient with ALS-FTD: a longitudinal MRI - PET multimodal study

15/09/2020
ALS


Telemedicine for patients with amyotrophic lateral sclerosis during COVID-19 pandemic: an Italian ALS referral center experience

15/09/2020
ALS


Amide signal intensities may be reduced in the motor cortex and the corticospinal tract of ALS patients

10/09/2020
ALS


Multiplexed chemogenetics in astrocytes and motoneurons restore blood-spinal cord barrier in ALS

09/09/2020
ALS


Efficient and rapid conversion of human astrocytes and ALS mouse model spinal cord astrocytes into motor neuron-like cells by defined small molecules

07/09/2020
ALS


Compensation of heat load deformations using adaptive optics for the ALS upgrade: a wave optics study

02/09/2020
ALS


C9orf72 loss-of-function: a trivial, stand-alone or additive mechanism in C9 ALS/FTD?

02/09/2020
ALS


Incremental Gains in the Battle against ALS

02/09/2020
ALS


Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression

01/09/2020
ALS


Development of LNA Gapmer Oligonucleotide-Based Therapy for ALS/FTD Caused by the C9orf72 Repeat Expansion

01/09/2020
ALS


The role of acid-labile subunit (ALS) in the modulation of GH-IGF-I action

31/08/2020
ALS


Dipeptide repeat protein and TDP-43 pathology along the hypothalamic-pituitary axis in C9orf72 and non-C9orf72 ALS and FTLD-TDP cases

31/08/2020
ALS


Differential Loss of Spinal Interneurons in a Mouse Model of ALS

30/08/2020
ALS


Properties of Glial Cell at the Neuromuscular Junction are Incompatible with synaptic repair in the SOD1(G37R) ALS mouse model

29/08/2020
ALS


Molecular and Cellular Mechanisms Affected in ALS

28/08/2020
ALS


Consideration of C9orf72-associated ALS-FTD as a neurodevel-opmental disorder: insights from neuroimaging

28/08/2020
ALS


Relationship between smoking and ALS: Mendelian randomisation interrogation of causality

27/08/2020
ALS


Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD

27/08/2020
ALS


Differential Vulnerability of Oculomotor Versus Hypoglossal Nucleus During ALS: Involvement of PACAP

27/08/2020
ALS


Paraspeckle components NONO and PSPC1 are not mislocalized from motor neuron nuclei in sporadic ALS

26/08/2020
ALS


The role of managed care professionals in improving care for patients with ALS

25/08/2020
ALS


The RNA exosome complex degrades expanded hexanucleotide repeat RNA in C9orf72 FTLD/ALS

24/08/2020
ALS


Investigation of resistant level to tribenuron-methyl, diversity and regional difference of the resistant mutations on acetolactate synthase (ALS) isozymes in Descurainia sophia L. from China

24/08/2020
ALS


A novel method for predicting the progression rate of ALS disease based on automatic generation of probabilistic causal chains

24/08/2020
ALS


Expression of acid-labile subunit (als) in developing and adult zebrafish and its role in dorso-ventral patterning during development

24/08/2020
ALS


RNA-mediated toxicity in C9orf72 ALS and FTD

24/08/2020
ALS


Chronic stress induces formation of stress granules and pathological TDP-43 aggregates in human ALS fibroblasts and iPSC-motoneurons

23/08/2020
ALS


Reappraisal of an ALS trial: unaccounted procedural risk

22/08/2020
ALS


Cell-Free Extracellular Vesicles Derived from Human Bone Marrow Endothelial Progenitor Cells as Potential Therapeutics for Microvascular Endothelium Restoration in ALS

21/08/2020
ALS


Effects of MSC-NTF cells on T and B regulatory cell function in ALS

18/08/2020
ALS


Modeling ALS using iPSCs: Is it possible to reproduce the phenotypic variations observed in patients in vitro?

17/08/2020
ALS


An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress

17/08/2020
ALS


Exome Chip Analysis of 14,026 Koreans Reve-als Known and Newly Discovered Genetic Loci Associated with Type 2 Diabetes Mellitus

14/08/2020
ALS


Identity by descent analysis identifies founder events and links SOD1 familial and sporadic ALS cases

14/08/2020
ALS


Pro-Oxidant Activity of an ALS-Linked SOD1 Mutant in Zn-Deficient Form

13/08/2020
ALS


In Familial ALS, Antisense Agent Reduces Disease-Related Proteins

12/08/2020
ALS


Effects of RAGE inhibition on the progression of the disease in hSOD1(G93A) ALS mice

11/08/2020
ALS


Amyotrophic lateral sclerosis with a heterozygous D91A SOD1 variant and classical ALS-TDP neuropathology

09/08/2020
ALS


No association between proton pump inhibitor use and ALS risk: a nationwide nested case-control study

09/08/2020
ALS


Opening the door to gene therapy for ALS

09/08/2020
ALS


Pathophysiological Implications of RNP Granules in Frontotemporal Dementia and ALS

08/08/2020
ALS


Inclusion Formation and Toxicity of the ALS Protein RGNEF and Its Association with the Microtubule Network

08/08/2020
ALS


The Relationship between Selected Demographic Factors and Speech Organ Dysfunction in Sporadic ALS Patients

08/08/2020
ALS


The Edinburgh Cognitive and Behavioural ALS Screen (ECAS) for Japanese ALS and FTD patients

07/08/2020
ALS


Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD

06/08/2020
ALS


Passive Transfer of Sera from ALS Patients with Identified Mutations Evokes an Increased Synaptic Vesicle Number and Elevation of Calcium Levels in Motor Axon Terminals, Similar to Sera from Sporadic Patients

06/08/2020
ALS


Repeated Application of Autologous Bone Marrow-Derived Lineage-Negative Stem/Progenitor Cells-Focus on Immunological Pathways in Patients with ALS

05/08/2020
ALS


Is it accurate to classify ALS as a neuromuscular disorder?

04/08/2020
ALS


Ablation of C9orf72 together with excitotoxicity induces ALS in rats

04/08/2020
ALS


Astrocyte regional diversity in ALS includes distinct aberrant phenotypes with common and causal pathological processes

03/08/2020
ALS


The Impact of ALS-Associated Genes hnRNPA1, MATR3, VCP and UBQLN2 on the Severity of TDP-43 Aggregation

31/07/2020
ALS


Phase Separation of Toxic Dipeptide Repeat Proteins Related to C9orf72 ALS/FTD

31/07/2020
ALS


Metformin treatment of the C9orf72 ALS/FTD mouse: Almost too good for words

30/07/2020
ALS


Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model

28/07/2020
ALS


Elevated exosomal secretion of miR-124-3p from spinal neurons positively associates with disease severity in ALS

27/07/2020
ALS


Raman mapping coupled to self-modelling MCR-ALS analysis to estimate active cosmetic ingredient penetration profile in skin

24/07/2020
ALS


Metformin inhibits RAN translation through PKR pathway and mitigates disease in C9orf72 ALS/FTD mice

24/07/2020
ALS


Identifying Putative Cerebrospinal Fluid Biomarkers of ALS in a North Indian population

24/07/2020
ALS


It Takes Two to Tango: DPRs in ALS and SCA36

24/07/2020
ALS


ALS: Management Problems

24/07/2020
ALS


ALS: Management Problems

24/07/2020
ALS


It Takes Two to Tango: DPRs in ALS and SCA36

24/07/2020
ALS


Identifying Putative Cerebrospinal Fluid Biomarkers of ALS in a North Indian population

22/07/2020
ALS


Metformin inhibits RAN translation through PKR pathway and mitigates disease in C9orf72 ALS/FTD mice

21/07/2020
ALS


Species identification, phylogenetic analysis and detection of herbicide-resistant biotypes of Amaranthus based on ALS and ITS

18/07/2020
ALS


Raman mapping coupled to self-modelling MCR-ALS analysis to estimate active cosmetic ingredient penetration profile in skin

18/07/2020
ALS


G(4)C(2) Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD

17/07/2020
ALS


Total serum immunoglobulin A in ALS

16/07/2020
ALS


Differentiating needs of informal caregivers of individuals with ALS across the caregiving course: a systematic review

16/07/2020
ALS


Generation of an ALS human iPSC line KEIOi001-A from peripheral blood of a Charcot disease-affected patient carrying TARDBP p.N345K heterozygous SNP mutation

16/07/2020
ALS


Thorn-shaped astrocytes in the depth of cortical sulci in Western Pacific ALS/Parkinsonism-Dementia complex

16/07/2020
ALS


Pattern of paresis in ALS is consistent with the physiology of the corticomotoneuronal projections to different muscle groups

16/07/2020
ALS


Phenotypic and genotypic features of patients diagnosed with ALS in the city of Sakarya, Turkey

16/07/2020
ALS


(no title)

16/07/2020
ALS


Pattern of paresis in ALS is consistent with the physiology of the corticomotoneuronal projections to different muscle groups

15/07/2020
ALS


Generation of an ALS human iPSC line KEIOi001-A from peripheral blood of a Charcot disease-affected patient carrying TARDBP p.N345K heterozygous SNP mutation

14/07/2020
ALS


Thorn-shaped astrocytes in the depth of cortical sulci in Western Pacific ALS/Parkinsonism-Dementia complex

14/07/2020
ALS


Clinical characteristics in young-adult ALS - results from a Portuguese cohort study

14/07/2020
ALS


Application of augmentation method to MCR-ALS analysis for XAFS and Raman data matrices in structural change of isopolymolybdates

14/07/2020
ALS


Differentiating needs of informal caregivers of individuals with ALS across the caregiving course: a systematic review

13/07/2020
ALS


OMICS-BASED EXPLORATION AND FUNCTIONAL VALIDATION OF NEUROTROPHIC FACTORS AND HISTAMINE AS THERAPEUTIC TARGETS IN ALS

13/07/2020
ALS


ALS is a multistep process in South Korean, Japanese, and Australian patients

11/07/2020
ALS


A prospective harmonized multicentre DTI study of cerebral white matter degeneration in ALS

10/07/2020
ALS


Validation of MRI biomarker of white matter degeneration for ALS clinical trials: One small step

10/07/2020
ALS


Phase 1-2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS

09/07/2020
ALS


SOD1 Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS

09/07/2020
ALS


The Beginning of Genomic Therapies for ALS

09/07/2020
ALS


Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD

08/07/2020
ALS


Targeted next-generation sequencing study in familial ALS-FTD Portuguese patients negative for C9orf72 HRE

08/07/2020
ALS


ALS, a cellular whodunit on motor neuron degeneration

07/07/2020
ALS


Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP-43-related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and Amyotrophic Lateral Sclerosis (ALS)

06/07/2020
ALS


A placebo-controlled trial to investigate the safety and efficacy of Penicillin G/Hydrocortisone in patients with ALS (PHALS trial)

06/07/2020
ALS


Exciting Complexity: The Role of Motor Circuit Elements in ALS Pathophysiology

06/07/2020
ALS


Dysregulation of steroid hormone receptors in motor neurons and glia associates with disease progression in ALS mice

05/07/2020
ALS


Quantitative patterns of motor cortex proteinopathy across ALS genotypes

03/07/2020
ALS


MCR-ALS analysis of (1)H NMR spectra by segments to study the zebrafish exposure to acrylamide

03/07/2020
ALS


Correction to: Divergence, Convergence, and Therapeutic Implications: A Cell Biology Perspective of C9ORF72-ALS/FTD

02/07/2020
ALS


Downregulated miR-18b-5p triggers apoptosis by inhibition of calcium signaling and neuronal cell differentiation in transgenic SOD1 (G93A) mice and SOD1 (G17S and G86S) ALS patients

01/07/2020
ALS


Mutations in the SIGMAR1 gene cause a distal hereditary motor neuropathy phenotype mimicking ALS: Report of two novel variants

30/06/2020
ALS


Resistance to acetolactate synthase inhibitors is due to a W 574 to L amino acid substitution in the ALS gene of redroot pigweed and tall waterhemp

30/06/2020
ALS


Measuring quality of life in ALS/MND: validation of the WHOQOL-BREF

29/06/2020
ALS


Absence of subcerebral projection neurons is beneficial in a mouse model of ALS

26/06/2020
ALS


Revisiting the complex architecture of ALS in Turkey: Expanding genotypes, shared phenotypes, molecular networks, and a public variant database

25/06/2020
ALS


Needling the future in ALS

20/06/2020
ALS


Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS

20/06/2020
ALS


Spreading in ALS: The relative impact of upper and lower motor neuron involvement

19/06/2020
ALS


Levels of clusterin, CD5L, ficolin-3, and gelsolin in ALS patients and controls

19/06/2020
ALS


Lemon Balm Extract ALS-L1023 Regulates Obesity and Improves Insulin Sensitivity via Activation of Hepatic PPARα in High-Fat Diet-Fed Obese C57BL/6J Mice

18/06/2020
ALS


The conserved multi-functional nuclear protein dss-1/Sem1 is required for C9orf72-associated ALS/FTD dipeptide toxicity

18/06/2020
ALS


Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls

11/06/2020
ALS


Improved ALS clinical trials through frequent at-home self-assessment: a proof of concept study

09/06/2020
ALS


Cell-Clearing Systems Bridging Repeat Expansion Proteotoxicity and Neuromuscular Junction Alterations in ALS and SBMA

09/06/2020
ALS


Divergence, Convergence, and Therapeutic Implications: A Cell Biology Perspective of C9ORF72-ALS/FTD

09/06/2020
ALS


ALS/FTD mutations in UBQLN2 impede autophagy by reducing autophagosome acidification through loss of function

09/06/2020
ALS


The Electrophysiological Determinants of Corticospinal Motor Neuron Vulnerability in ALS

08/06/2020
ALS


Abnormal Serum Iron-Status Indicator Changes in Amyotrophic Lateral Sclerosis (ALS) Patients: A Meta-Analysis

08/06/2020
ALS


Disease propagation in amyotrophic lateral sclerosis (ALS): an interplay between genetics and environment

08/06/2020
ALS


Malnutrition at diagnosis in amyotrophic lateral sclerosis (als) and its influence on survival: Using glim criteria

08/06/2020
ALS


5-HT2A/B receptor expression in the phrenic motor nucleus in a rat model of ALS (SOD1(G93A))

08/06/2020
ALS


In vivo histopathological staging in C9orf72-associated ALS: A tract of interest DTI study

08/06/2020
ALS


Intralingual administration of AAVrh10-miRSOD1 improves respiratory but not swallowing function in a SOD1 mouse model of ALS

05/06/2020
ALS


Tau Accumulation via Reduced Autophagy Mediates GGGGCC Repeat Expansion-Induced Neurodegeneration in Drosophila Model of ALS

05/06/2020
ALS


Common mutations of interest for the diagnosis of amyotrophic lateral sclerosis: how common are common mutations in ALS genes?

05/06/2020
ALS


Blowing Hot and Cold in ALS: The Duality of TBK1

05/06/2020
ALS


From basic research to the clinic: innovative therapies for ALS and FTD in the pipeline

03/06/2020
ALS


Tau deposition in the spinal cord is not specific for CTE-ALS

03/06/2020
ALS


Synaptic restoration by cAMP/PKA drives activity-dependent neuroprotection to motoneurons in ALS

03/06/2020
ALS


Correction: Vascular regression precedes motor neuron loss in the FUS (1-359) ALS mouse model

02/06/2020
ALS


FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention

01/06/2020
ALS


CRISPR/Cas9-Mediated Gene Correction to Understand ALS

31/05/2020
ALS


Tailored treatment for ALS poised to move ahead

29/05/2020
ALS


Differences between South African and Portuguese ALS cohorts from an environmental perspective

28/05/2020
ALS


Regulation of ALS-Associated SOD1 Mutant SUMOylation and Aggregation by SENP and PIAS Family Proteins

28/05/2020
ALS


Detection of melamine and sucrose as adulterants in milk powder using near-infrared spectroscopy with DD-SIMCA as one-class classifier and MCR-ALS as a means to provide pure profiles of milk and of both adulterants with forensic evidence: A short communic

28/05/2020
ALS


Detection of melamine and sucrose as adulterants in milk powder using near-infrared spectroscopy with DD-SIMCA as one-class classifier and MCR-ALS as a means to provide pure profiles of milk and of both adulterants with forensic evidence: A short communic

28/05/2020
ALS


Detection of melamine and sucrose as adulterants in milk powder using near-infrared spectroscopy with DD-SIMCA as one-class classifier and MCR-ALS as a means to provide pure profiles of milk and of both adulterants with forensic evidence: A short communic

27/05/2020
ALS


Detection of melamine and sucrose as adulterants in milk powder using near-infrared spectroscopy with DD-SIMCA as one-class classifier and MCR-ALS as a means to provide pure profiles of milk and of both adulterants with forensic evidence: A short communic

27/05/2020
ALS


ASC-Exosomes Ameliorate the Disease Progression in SOD1(G93A) Murine Model Underlining Their Potential Therapeutic Use in Human ALS

27/05/2020
ALS


The Role of the Microbiota-Gut-Brain Axis and Antibiotics in ALS and Neurodegenerative Diseases

27/05/2020
ALS


Detection of melamine and sucrose as adulterants in milk powder using near-infrared spectroscopy with DD-SIMCA as one-class classifier and MCR-ALS as a means to provide pure profiles of milk and of both adulterants with forensic evidence: A short communic

27/05/2020
ALS


Mitigation of ALS pathology by neuron-specific inhibition of nuclear factor kappa B signaling

27/05/2020
ALS


Author Correction: De novo design of RNA-binding proteins with a prion-like domain related to ALS/FTD proteinopathies

27/05/2020
ALS


Mechanisms Regulating the UPS-ALS Crosstalk: The Role of Proteaphagy

23/05/2020
ALS


Auditory Electrooculogram-based Communication System for ALS Patients in Transition from Locked-in to Complete Locked-in State

22/05/2020
ALS


Advance care planning and mental capacity in ALS: a current challenge for an unsolved matter

21/05/2020
ALS


Neuroprotective Fragment C of Tetanus Toxin Modulates IL-6 in an ALS Mouse Model

20/05/2020
ALS


Optimizing Telemedicine to Facilitate ALS Clinical Trials

17/05/2020
ALS


Mutant TDP-43 Expression Triggers TDP-43 Pathology and Cell Autonomous Effects on Primary Astrocytes: Implications for Non-cell Autonomous Pathology in ALS

15/05/2020
ALS


Frameshift peptides alter the properties of truncated FUS proteins in ALS-FUS

14/05/2020
ALS


Diagnostic delay among ALS patients: Egyptian study

14/05/2020
ALS


Understanding the needs of people with ALS: a national survey of patients and caregivers

14/05/2020
ALS


Burden of Rare Variants in ALS and Axonal Hereditary Neuropathy Genes Influence Survival in ALS: Insights from a Next Generation Sequencing Study of an Italian ALS Cohort

14/05/2020
ALS


Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V

14/05/2020
ALS


A proposal for new diagnostic criteria for ALS

12/05/2020
ALS


Photostability study of multicomponent drug formulations via MCR-ALS: The case of the hydrochlorothiazide-amiloride mixture

12/05/2020
ALS


Validation of serum neurofilaments as prognostic and potential pharmacodynamic biomarkers for ALS

09/05/2020
ALS


Oligogenicity, C9orf72 expansion, and variant severity in ALS

09/05/2020
ALS


How I managed to stop the progression of ALS

09/05/2020
ALS


Transmission of ALS pathogenesis by the cerebrospinal fluid

08/05/2020
ALS


ALS/FTD-associated protein FUS induces mitochondrial dysfunction by preferentially sequestering respiratory chain complex mRNAs

08/05/2020
ALS


Studying ALS: Current Approaches, Effect on Potential Treatment Strategy

08/05/2020
ALS


Presynaptic Homeostasis Opposes Disease Progression in Mouse Models of ALS-Like Degeneration: Evidence for Homeostatic Neuroprotection

08/05/2020
ALS


Functional characterization of a FUS mutant zebrafish line as a novel genetic model for ALS

08/05/2020
ALS


Proteomics-Based Approach Identifies Altered ER Domain Properties by ALS-Linked VAPB Mutation

07/05/2020
ALS


Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo

07/05/2020
ALS


Skeletal-Muscle Metabolic Reprogramming in ALS-SOD1(G93A) Mice Predates Disease Onset and Is A Promising Therapeutic Target

06/05/2020
ALS


Does the presenting phenotype predict survival in ALS-FTD?

05/05/2020
ALS


REM sleep physiology and selective neuronal vulnerability in amyotrophic lateral sclerosis

05/05/2020
ALS


In vivo stress granule misprocessing evidenced in a FUS knock-in ALS mouse model

03/05/2020
ALS


CCR2 is localized in microglia and neurons, as well as infiltrating monocytes, in the lumbar spinal cord of ALS mice

01/05/2020
ALS


Proteome Homeostasis Dysfunction: A Unifying Principle in ALS Pathogenesis

01/05/2020
ALS


Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment

30/04/2020
ALS


Application of the area correlation constraint in the MCR-ALS quantitative analysis of complex mixture samples

29/04/2020
ALS


Cytoplasmic localization of amyotrophic lateral sclerosis (ALS)-related TDP-43 proteins modulates stress-granule formation

29/04/2020
ALS


Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment

29/04/2020
ALS


Preparation and characterization of metformin hydrochloride controlled-release tablet using fatty acid coated granules

28/04/2020
ALS


Parkinsonism in C9orf72 expansion without co-existing Lewy body pathology; a case report and review of the literature

28/04/2020
ALS


A comparative study of South African and Portuguese amyotrophic lateral sclerosis cohorts

28/04/2020
ALS


CAG repeats ≥ 34 in Ataxin-1 gene are associated with amyotrophic lateral sclerosis in a Brazilian cohort

28/04/2020
ALS