Gastric adenocarcinoma arising in gastrocystoplasty

Bladder Cancer

Urology. 2020 Jul 16:S0090-4295(20)30844-X. doi: 10.1016/j.urology.2020.07.003. Online ahead of print.


Gastric cancer is a rare long-term complication in gastrocystoplasty. We report two cases of gastric adenocarcinoma and review the literature for similar cases. A total of 14 cases are identified. The majority of patients are males, presented with hematuria, and developed cancer at a younger age, more than 10 years after gastrocystoplasty. Long-term follow up information was limited, but 5 patients (36%) died within five years of diagnosis. Annual surveillance for malignancy may not be effective

due to its rarity. However, symptomatic patients, particularly those 10 years after the surgery, warrant detailed evaluation to rule out neoplastic transformation.