Br J Dermatol. 2020 Jul 30. doi: 10.1111/bjd.19426. Online ahead of print.
While cutaneous T-cell lymphoma (CTCL) presents most commonly with a CD4+ phenotype, CD8+ and CD30+ variants have also been described. CD8+ variants include primary cutaneous epidermotropic cytotoxic T-cell lymphoma, subcutaneous panniculitis-like T-cell lymphoma, cutaneous CD8+ lymphomas associated with immunodeficiency, and CD8+ variants of other well-defined CTCLs1 . While the epidemiology of other CTCLs has been well described, there remains a dearth of literature characterizing the incidence and survival patterns of CD8+ CTCL2 . Thus, we aimed to better characterize data on US national epidemiologic trends of this diverse group of malignancies using the Surveillance, Epidemiology, and End Results (SEER) database.